Accelagen™: Surgical Collagen Matrix
Because Every Surgical Wound Deserves the Best Care
The Journey of Innovation: Berkeley Advanced Biomaterials
Founded in 1996 and headquartered in Berkeley, California, Berkeley Advanced Biomaterials (BAB) is a leading developer and manufacturer of high-quality, cost-effective biomaterials. Specializing in biologics for skeletal repair and wound management, BAB's products are widely used in orthopedic, spine, dental, and other surgical applications.
Accelagen surgical powder represents an innovative approach to wound management leveraging the natural properties of collagen to enhance healing. Accelagen does this by providing a scaffold for cellular growth, promoting tissue regeneration, and enhancing biocompatibility and biodegradability.
What is Accelagen™?
Accelagen™ is an advanced collagen matrix made from highly purified bovine Type I collagen. Its unique powder-to-gel consistency allows for easy application and superior wound bed conformity, creating an optimal healing environment.
The product transforms upon contact with wound exudate, conforming perfectly to wound contours while maintaining a moist environment that accelerates healing and tissue regeneration.
Key Features & Benefits
Native, Non-Hydrolyzed Collagen
Maintains bioactivity to promote fibroblast activity while reducing inflammation and scarring. Preserves the natural structure essential for optimal wound healing.
Low-pH Formulation
Increases fibroblast proliferation, stimulates healing processes, shields against microbial growth, and provides antimicrobial defense in the wound environment.
Gel Formation
Creates and maintains a moist wound environment for optimal regeneration, conforming perfectly to wound contours while supporting cellular migration.
How Accelagen™ Works
Mechanism of Action
  • Promotes extracellular matrix formation and accelerates tissue regeneration
  • Maintains an acidic microenvironment that discourages bacterial growth
  • Enhances cell migration and boosts collagen synthesis
  • Reduces pain, inflammation, and scarring
Scientific Basis
The role of pH in wound healing is well-documented in scientific literature. Accelagen's low-pH environment creates optimal conditions for healing while providing antimicrobial protection.
Collagen supports healing through multiple pathways: facilitating cellular migration, attracting growth factors, and creating a scaffold for new tissue formation.
Indications & Application
1
Indications for Use
  • Surgical Wounds
  • Partial and full-thickness wounds
  • Pressure ulcers (I-IV), venous ulcers, mixed etiology ulcers
  • Diabetic ulcers, stasis ulcers
  • First and second-degree burns
  • Cuts, abrasions, surgical wounds
2
Application Guide
  1. Prepare the surgical site according to standard protocol
  1. Apply Accelagen™ powder directly to the wound bed
  1. Cover with appropriate dressing per standard protocol
  1. Monitor and reapply as needed during dressing changes
Clinical Evidence & Product Information
Research Highlights
Clinical studies demonstrate that Accelagen™ delivers faster epithelialization, increased collagen deposition, reduced inflammation, and lower bacterial burden compared to standard care.
Research confirms that low-pH environments speed healing and suppress infection, while collagen dressings significantly improve outcomes for both chronic and acute wounds.
Product Options
Meet Our Leadership Team
Our team brings a wealth of experience and expertise from across the biologics, orthopedics, spine, trauma, and wound care sectors, ensuring Accelagen™ remains at the forefront of surgical innovation.
Danielle Kelley
CEO
With extensive leadership in the orthopedic device and biologics sectors, Danielle drives strategic vision and growth for Accelagen. Her expertise spans orthopedics, spine, and advanced wound care, ensuring market innovation.
Mesfin Mengesha
President
Mesfin brings a wealth of experience in operations and product development for biomaterials. His background includes significant contributions to wound, spine, and trauma solutions, optimizing manufacturing and market delivery.
Michele DiCarlo
Director of Sales
Michele leads the sales strategy with a deep understanding of surgical markets. Her proven track record in biologics and wound care sales ensures strong partnerships and expanding market reach across diverse surgical specialties.
Drew Leachman
Sales Director East
Drew excels in building relationships and driving sales in the Eastern region. Specializing in orthopedic and trauma products, he connects surgeons with effective wound management and biologics solutions, fostering strong client engagement.
Vacant
Sales Director West
This role is critical for expanding our presence in the Western market. We are seeking an experienced leader with a strong background in biologics, orthopedics, and wound care to drive sales and foster key relationships.
Steve Panek
Director of National Accounts
Steve manages key national accounts, leveraging his vast experience in orthopedic, trauma and wound care. His strategic approach ensures major healthcare systems benefit from Accelagen’s advanced biologics for optimal patient outcomes.
Contact & Support
Departmental Contacts
  • Sales & Distributor Development: Michele DiCarlo
  • East Sales Director: Drew Leachman
  • West Sales Director: Vacant
  • National Accounts: Stephen Panek
  • Berkeley Advance Biomaterials Main#: (510) 883-0500
Berkeley Advanced Biomaterials is committed to innovation, quality, and comprehensive clinical support for all our advanced wound care solutions.

More Information
Visit the Berkeley Advanced Biomaterials website for more information on our company, certificates and licenses.
Contact sales for product brochures, clinical studies, and review articles.
BAB Website